by Lane Lenard PhD on 13/02/10 at 1:39 pm
Bisphosphonates are now the most widely marketed and prescribed patented, FDA-approved anti-osteoporosis drugs. Bisphosphonates mimic, to some extent, the effects of estrogen on bone in that they work by inhibiting bone resorption [the process by which old bone is removed to make room for new bone]. However, like estrogen, these drugs have no ability to build new bone.
Currently FDA-approved bisphosphonates, including Fosamax (alendronate), Actonel (risedronate), Didronel (etidronate), Boniva (ibandronate), and Reclast (Zometa) (zoledronate), are designed to strengthen bone by inhibiting normal osteoclastic bone resorbing activity, which slows the loss of bone mineral density (BMD), allowing the trabecular architecture to stabilize. Notice that this has nothing to do with stabilizing the balance between estrogen and progesterone, restoring calcium levels, or any other natural process.
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"My mother is 76 years old and was taking Fosamax and Boniva for over 8 years. She too fractured her femur just walking down 2 steps it happened out of nowhere. She had a rod put in because the fracture never healed itself and the Dr. warned her it could break at any moment as well as the other side. She suffered a lot of pain and was in the hospital for 1 week, rehab nursing care for 3 weeks, at home rehab for 2 months now and still walking with a walker in fear of falling at any moment if the other side fractures. She has pain every day and the Dr. told her it was all from the two drugs she was taking. Its a damn shame what this drug has done to my mom it has destroyed her life. She will never be the same active woman she once was."
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